Advances in Orthopedics / 2015 / Article / Tab 1

Clinical Study

Long Term Anticoagulation (4–16 Years) Stops Progression of Idiopathic Hip Osteonecrosis Associated with Familial Thrombophilia

Table 1

Six patients, 9 hips (5 heterozygous for the V Leiden mutation, 1 with resistance to activated protein C). Anticoagulation for 4 to 16 years. Symptoms, nonprogression by X-ray, and Ficat stages at entry and on follow-up.

PatientRace
sex
Age at entryFollow-up yrsSymptom improvement on long term anticoagulationProgression by X-rayFicat stages at entry and on follow-up

Number 1
(2 hips)
WM564Symptom-free hips in 9 months
No restriction in activities
Full range of motion
None in both hipsFicat II, right hip, Ficat I, left hip, unchanged

Number 2
(right hip)
WF294Symptom-free right hip in 3 months
No restriction in activities
None in right hipFicat II, right hip, unchanged

Number 3
(2 hips)
WM489Symptoms persistent in both hips requiring Percocet
No restriction in activities
Full range of motion
None in both hipsFicat II, both hips, unchanged

Number 4
(right hip)
BF6913Symptom-free right hip in 16 months
No restriction in activities
Full range of motion
None in right hipFicat II, right hip, unchanged

Number 5
(2 hips)
WM4913Symptom-free hips in 3 months
No restriction in activities
Full range of motion including rollerblading
None in both hipsFicat II, both hips, unchanged

Number 6
(right hip)
WM3216Symptom-free right hip in 3 months
No restriction in activities
Full range of motion including weight-lifting
None in right hip Ficat II, right hip, unchanged