High Baseline CD4 Count and Exclusive Breastfeeding Are Associated with Lower Rates of Mother to Child HIV Transmission in Northwestern Uganda: A Two-Year Retrospective Cohort Study
Table 3
Multivariate logistic regression analysis of factors associated with MTCT at ARRH, Northwestern Uganda.
Variable
MTCT along the EID cascade?
Multivariable logistic regression analysis
-value
No (No., %)
Yes (No., %)
AOR (95% CI)
Overall
270 (91.5)
25 (8.5)
Attended ANC during pregnancy
No
107 (85.6)
18 (14.4)
Ref
Yes
163 (95.9)
7 (4.1)
0.55 (0.18–1.70)
0.298
CD4 level (Cells/ml) at enrolment
<350
65 (83.3)
13 (16.7)
Ref
350–500
45 (95.7)
2 (4.3)
0.30 (0.05–1.65)
0.167
>500
160 (94.1)
10 (5.9)
0.29 (0.10–0.85)
0.024
Place of delivery
Health facility
192 (94.1)
12 (5.9)
Ref
Home
78 (85.7)
13 (14.3)
1.56 (0.57–4.30)
0.389
Nevirapine initiation after delivery
Never at all
22 (62.9)
13 (37.1)
Ref
After 6-weeks
3 (100.0)
0 (0.0)
1
From birth up to 6-weeks
245 (95.3)
12 (4.7)
2.50 (0.75–8.30)
0.133
Exclusive breastfeeding in first 6-months
No
33 (66.0)
17 (34.0)
Ref
Yes
237 (96.7)
8 (3.3)
0.17 (0.52–0.55)
0.003
Maternal use of ART
Never on ART
5 (62.5)
3 (37.5)
Ref
Received ART during labor and delivery
6 (54.6)
5 (45.4)
2.01 (0.21–19.5)
0.545
On life-long ART
259 (93.8)
17 (6.2)
0.72 (0.10–5.12)
0.742
Note. Percentages calculated as row percentages (n/N); ANC: antenatal care; AOR: adjusted odds ratio; ART: antiretroviral therapy; HAART: highly active ART; MTCT: mother to child transmission; NVP: Nevirapine; UOR: unadjusted odds ratio; X: adjusted for all statistically significant variables at unadjusted analysis; Ref: reference category.
