Effect of Simvastatin on Arterial Stiffness in Patients with Statin Myalgia

Figure 1

Data are means ± SD. (a) Central pulse wave velocity (PWV) before (Pre) and after (Post) 8 wks of simvastatin () or placebo treatment (); compared to Pre within a group. (b) Changes (Post-Pre) in central PWV of participants who completed the simvastatin intervention with no development of statin-related muscle symptoms (nonmyalgics; ) compared with those who reported muscle symptoms with daily simvastatin treatment (myalgics; ); between groups.

(a)

(b)