Clinical Study

Effect of Simvastatin on Arterial Stiffness in Patients with Statin Myalgia

Table 1

Baseline characteristics of participants by myalgia statusa,b,c.

Nonmyalgic sample ()Myalgic sample ()

Age, y60.9 ± 8.559.1 ± 10.0
Men, (%)42 (55%)25 (66%)
Height, m1.7 ± 0.11.7 ± 0.1
Weight, kg80.8 ± 15.887.4 ± 17.9
BMI, kg/m227.7 ± 4.229.8 ± 5.2
SBP, mmHg123.4 ± 13.7121.5 ± 13.1
DBP, mmHg74.9 ± 6.475.1 ± 6.9
Time on simvastatin, wks7.3 ± 1.63.8 ± 2.0
TC, mmol/L6.56 ± 1.146.35 ± 1.04
LDL-C, mmol/L4.23 ± 1.004.11 ± 0.80
HDL-C, mmol/L1.41 ± 0.381.33 ± 0.39
TG, mmol/L4.51 ± 2.854.57 ± 2.98

aData are means ± SD or proportions. bBMI, body mass index; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides. cPlasma lipid levels assessed prior to initiating simvastatin or placebo treatment did not differ () and therefore were averaged. between samples.