Effect of Simvastatin on Arterial Stiffness in Patients with Statin Myalgia

Table 3

Arterial stiffness changes by drug assignment^a,b.

	Simvastatin		Placebo
	Baseline	Study end	Baseline	Study end
Peripheral PWV, m/s	10.3 ± 1.9	10.4 ± 1.8	10.7 ± 2.5	10.2 ± 1.7
Central SBP, mmHg	115.1 ± 14.6	112.7 ± 11.6	113.3 ± 12.2	112.1 ± 13.3
Central DBP, mmHg	75.7 ± 6.9	75.1 ± 7.6	74.9 ± 6.9	74.5 ± 8.9
AP, mmHg	11.9 ± 6.4	11.4 ± 5.0	12.1 ± 5.2	10.9 ± 5.2
AIx, %	23.4 ± 9.4	23.5 ± 8.9	24.9 ± 9.4	23.0 ± 8.9

^aData are means ± SD (). ^bAIx, augmentation index; AP, augmentation pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure; PWV, pulse wave velocity. There were no differences at baseline () between nonmyalgic and myalgic participants within a treatment group.