Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation

Figure 6

MiaPaCa-2 cells were treated with or without Tq (50 μM) for 12–48 h. HDACs activity decreased significantly at 24 and 48 h. Values are expressed as mean ± standard deviation of three different observations. versus control levels, using one-way repeated ANOVA with subsequent all pairwise comparison procedure by Student’s -test.