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Advances in Preventive Medicine
Volume 2016 (2016), Article ID 9405105, 13 pages
Research Article

Prevalence and Associated Factors of Insulin Resistance in Adults from Maracaibo City, Venezuela

1Endocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo 4004, Venezuela
2Morphologic Sciences Department and Pediatric Surgery Department, School of Medicine, University of Zulia, Maracaibo 4004, Venezuela

Received 13 March 2016; Accepted 26 May 2016

Academic Editor: Gerardo E. Guillén Nieto

Copyright © 2016 Valmore Bermudez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background and Aim. Insulin resistance (IR) is a prominent pathophysiologic component in a myriad of metabolic disorders, including obesity, prediabetes, and type 2 diabetes mellitus, which are common in our locality. The objective of this study was to determine the prevalence of IR and factors associated with this condition in an adult population from Maracaibo city, Venezuela. Methodology. A cross-sectional, descriptive study with multistaged randomized sampling was carried out in 2026 adults. IR was defined as HOMA2-IR ≥ 2. A multiple logistic regression model was constructed in order to evaluate factors associated with IR. Results. The prevalence of IR was 46.5% (), with 46.7% () in the general population, 46.4% () in females, and 47.90% () in males (). IR prevalence tended to increase with age and was significantly greater in subjects aged ≥30 years (; ). Employment, alcohol consumption, obesity, high triacylglycerides, low HDL-C, and dysglycemia were associated with greater odds of IR, whereas a high level of physical activity appeared to be weak protective factor against IR. Conclusions. The prevalence of IR is elevated in our locality. The main determinants of this condition appear to be the presence of obesity, high triacylglycerides, low HDL-C, dysglycemia, and alcohol intake.