Clinical Study

Effect of Lycosome-Formulated Phosphatidylcholine on Parameters of Biological Oxidation after Single Intake of Moderate Amount of Alcohol

Table 4

Changes in serum malonic dialdehyde (MDA) and oxidized LDL (LDL-Px) levels (averages +/-SD). The volunteers were enrolled, screened, and randomized as described in the “Material and Methods” Section and given study products as well as alcohol-containing beverages. The parameters were measured at “0” hours and after 1, 2.5, and 5 hours following the intervention.

MDA MLDL-Px (E-460)

Time Points:Time Points:
Groups“0” Hour1 h2.5 h5 hGroups“0” Hour1 h2.5 h5 h

Alcohol Intake 0.5 ml/kg

Placebo 88.1±3.177.9±2.769.9±2.649.9±1.7Placebo218.9±3.6225.6±1.7237.4±2.8243.4±3.6

PC 90.4±3.371.3±1.960.5±3.240.3±2.5PC223.4±2.3227.6±2.1230.1±2.2228.4±2.7

PC+Lyc 87.3±2.966.0±1.648.1±2.025.1±2.3PC+Lyc225.6±2.7218.0±3.4210.4±3.0195.4±2.9

Alcohol Intake 1.0 ml/kg

Placebo 93.4±1.865.4±2.657.3±2.535.4±2.0Placebo216.7±2.7235.1±1.6245.6±1.6261.9±4.5

PC 91.6±2.357.4±1.954.2±2.630.3±3.1PC221.9±3.1225.6±2.0227.6±2.1231.7±3.7

PC+Lyc 89.4±1.253.1±2.142.3±1.419.3±2.6PC+Lyc220.0±2.6210.7±1.9207.0±3.6190.4±2.9