Advances in Preventive Medicine / 2019 / Article / Tab 2 / Review Article
Vitamin D as an Adjunctive Treatment to Standard Drugs in Pulmonary Tuberculosis Patients: An Evidence-Based Case Report Table 2 Critical appraisal of RCTs using the CEBM tool by the University of Oxford.
Author No. of Participants Level of Evidence Internal Validity Importance Randomisation Baseline Similarity Equally Treated Intention to Treat Blinding RR ARR ( ) RRR ( ) NNT 95 CI Afzal et al. (2018) [12 ] 120 2 + + + + - 1.11 10.0 11.3 10 (1.05, 1.26) Daley et al. (2015) [13 ] 247 2 + + + + + 1.02 12.0 17.4 83 (0.86, 1.18) Ganmaa et al. (2017) [14 ] 390 2 + + + + + 1.07 49.4 6.7 20 (0.96, 1.18) Martineau et al. (2011) [15 ] 108 2 + + + + + 0.98 15.1 18.8 66 (0.79, 1.17) Mily et al. (2015) [16 ] 127 2 + + + + + 1.15 94.7 15.4 11 (0.9, 1.4) Nursyam EW (2006) [17 ] 67 2 + + + + + 1.03 3.0 3.1 34 (0.9, 1.1) Ralph et al. (2013) [18 ] 79 2 + - + + + 0.99 0.4 0.7 222 (0.64, 1.34) Tukvadze et al. (2015) [19 ] 199 2 + + + + + 1.00 0.2 0.2 660 (0.88, 1.12)
Internal validity indicated by + stated clearly in the article; - not being done; ? not stated clearly
Importance was calculated based on the SCR at the 8th week of treatment.