Clinical and Histopathological Factors Associated with the Tumoral Expression of TGF-β1, MED15, CD16, and CD57 in Oral Squamous Cell Carcinoma

Table 2

Factors associated with the ΔΔCt CD16, calculated using the backward-selection stepwise log-level multiple linear regression.

Models and parameters		Unstandardized coefficients		Beta		95% CI		VIF
		B	SE			Low	Up
1	(Constant)	3.467	3.680		0.353	−4.020	10.953
	Sex: male	1.517	1.500	0.180	0.319	−1.535	4.569	1.602
	Age at diagnosis	−0.060	0.043	−0.219	0.170	−0.146	0.027	1.246
	Tumor size (mm)	−0.027	0.032	−0.164	0.414	−0.092	0.039	2.000
	Depth of invasion (mm)	0.082	0.049	0.292	0.107	−0.018	0.182	1.576
	Histology grade	0.324	1.114	0.048	0.773	−1.943	2.592	1.394
	Necrosis presence	0.473	1.573	0.047	0.766	−2.727	3.672	1.234
	Lymphatic invasion	0.294	2.426	0.029	0.904	−4.642	5.230	2.937
	Vascular invasion	−1.408	2.377	−0.134	0.558	−6.243	3.427	2.605
	Perineural invasion	−0.945	1.380	−0.111	0.498	−3.754	1.863	1.342
	Extracapsular nodal extension	0.818	2.784	0.048	0.771	−4.846	6.482	1.380
	Stage	−0.484	0.775	−0.115	0.537	−2.062	1.093	1.713
	Smoking	3.696	2.007	0.316	0.075	−0.387	7.780	1.494
8	(Constant)	4.038	2.528		0.118	−1.071	9.147
	Age at diagnosis	−0.067	0.037	−0.248	0.079	−0.143	0.008	1.072
	Tumor size (mm)	−0.031	0.026	−0.190	0.239	−0.083	0.021	1.442
	Depth of invasion (mm)	0.066	0.044	0.235	0.146	−0.024	0.155	1.432
	Vascular invasion	−1.671	1.441	−0.159	0.253	−4.584	1.242	1.074
	Smoking	4.555	1.569	0.389	0.006	1.385	7.726	1.023
9	(Constant)	4.455	2.513		0.084	−0.620	9.529
	Age at diagnosis	−0.077	0.036	−0.284	0.040	−0.151	−0.004	1.015
	Tumor size (mm)	−0.033	0.026	−0.204	0.207	−0.085	0.019	1.434
	Depth of invasion (mm)	0.065	0.044	0.234	0.149	−0.024	0.155	1.432
	Smoking	4.646	1.573	0.397	0.005	1.468	7.823	1.021

B, regression coefficient; SE, standard error; beta, standard regression coefficient; CI, confidence interval; VIF, variance inflation factor.