Association between ApoA1 Gene, Plasma Lipid Profile, hsCRP Level, and Risk of Arterial Stiffness in Thai Elderly

Table 5

Association between the ApoA1 polymorphism related to metabolic components and risk of arterial stiffness on the basis of the CAVI index.

		Crude OR (95% CI)	Adjusted OR (95% CI)^a
Metabolic syndrome	GG	Reference	Reference
	GA + AA	0.54 (0.28–1.04)	0.79 (0.36–1.46)
	value	0.681	0.375
Central obesity	GG	Reference	Reference
	GA + AA	0.72 (0.39–1.32)	0.91 (0.47–1.76)
	value	0.298	0.792
High blood pressure	GG	Reference	Reference
	GA + AA	1.52 (0.83–2.78)	1.85 (0.94–3.67)
	value	0.173	0.740
Hyperglycemia	GG	Reference	Reference
	GA + AA	0.69 (0.34–1.42)	0.90 (0.42–1.91)
	value	0.323	0.791
Hypertriglyceridemia	GG	Reference	Reference
	GA + AA	1.09 (0.52–1.93)	1.12 (0.55–2.27)
	value	0.978	0.737
Low HDL-C	GG	Reference	Reference
	GA + AA	0.474 (0.24–0.93)	0.59 (0.24–0.88)
	value	0.030	0.041
High hs-CRP level^b	GG	Reference	Reference
	GA + AA	0.30 (0.16–0.57)	0.28 (0.13–0.64)
	value	0.006	0.010

^aAdjusted OR calculated from the logistic regression adjusted for sex, age, BMI, smoking, and drinking. ^bGeometric mean of the hs-CRP level. ApoA1, apolipoprotein A1; CAVI, cardio-ankle vascular index; OR, odds ratio; CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein.