Advances in Pharmacological and Pharmaceutical Sciences / 2010 / Article / Fig 6

Research Article

The Role of Tetrahydrobiopterin and Dihydrobiopterin in Ischemia/Reperfusion Injury When Given at Reperfusion

Figure 6

Initial and final expressed in mmHg/s from different experimental groups. Hearts were perfused in the presence or absence of PMNs. PMNs induced a significant decrease in Neither BH4 (10  M) nor BH2 (100  M) treatment significantly improved compared to I/R+PMN hearts. All values are expressed as mean SEM. Numbers of hearts are at the bottom of the bars. All drugs are in μM concentrations. (NS, not significant compared to initial LVDP values).

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