Chronic Treatment with a Promnesiant GABA-A -Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model
Figure 6
QPCR expression level of selected IEGs. (a) Mean cumulated expression levels of five selected IEGs in euploid and Ts65Dn mice; (b) effect of Ξ±5IA treatment on the mean level of expression of five selected IEGs; (c) expression of c-Fos, Egr2, Bdnf, Homer-1, and Arc in the four genotype and treatment experimental groups. *, two-way ANOVA with Fisherβs post hoc comparisons; #, ###, and one-sample t-test.
