Research Article

Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

Table 2

Effect of metformin with placebo on FBG, PPBG, HbA1c, and plasma AA in patients with type 2 diabetes mellitus after 12 weeks of treatment.

ParameterBefore treatmentAfter treatment š‘ƒ (paired)

FBG 1 6 0 . 7 5 Ā± 2 . 6 0 1 5 5 . 3 3 Ā± 2 . 3 1 <0.05
PPBG 2 1 8 . 5 1 Ā± 3 . 5 3 2 1 1 . 5 7 Ā± 2 . 8 8 <0.05
HbA1c 8 . 1 8 Ā± 0 . 1 2 8 . 0 1 Ā± 0 . 1 1 >0.05
Plasma AA 0 . 2 4 Ā± 0 . 0 0 6 0 . 2 7 Ā± 0 . 0 1 >0.05

š‘› = 3 3 in number, FBG: fasting blood glucose, PPBG: postmeal blood glucose, HbA1c: glycosylated hemoglobin, plasma AA: plasma ascorbic acid. FBG, PPBG, and plasma AA are measured in mg/dL.