Research Article

Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

Table 3

Effect of metformin with vitamin C on FBG, PPBG, HbA1c and plasma AA in patients with type 2 diabetes mellitus after 12 weeks of treatment.

ParameterBefore treatmentAfter treatment š‘ƒ (paired)

FBG 1 5 7 . 6 3 Ā± 3 . 1 3 1 4 1 . 1 8 Ā± 3 . 8 1 <0.01
PPBG 2 2 2 . 2 4 Ā± 3 . 1 6 2 0 6 . 6 9 Ā± 3 . 3 1 <0.05
HbA1c 8 . 2 6 Ā± 0 . 0 9 7 . 8 0 Ā± 0 . 0 8 <0.01
Plasma AA 0 . 2 6 Ā± 0 . 0 0 8 0 . 4 5 Ā± 0 . 0 1 <0.001

š‘› = 3 3 in number, FBG: fasting blood glucose, PPBG: postmeal blood glucose, HbA1c: glycosylated hemoglobin, plasma AA: plasma ascorbic acid. FBG, PPBG, and plasma AA are measured in mg/dL.