A Comparison of the 2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain
Figure 1
GABAA receptor occupancy of (a) L-838,417 and (b) TPA023 in whole rat brain compared to drug concentrations in the plasma (nM free). Each datapoint represents an individual animal.