Research Article

A Comparison of the 𝜶 2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain

Figure 1

GABAA receptor occupancy of (a) L-838,417 and (b) TPA023 in whole rat brain compared to drug concentrations in the plasma (nM free). Each datapoint represents an individual animal.
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(a)
608912.fig.001b
(b)