Review Article

Neurosteroid Binding Sites on the GABAA Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence

Figure 5

Effects of intraperitoneal administration of DHEA on rats ( 𝑛 = 5 ) responding under an FR-10 schedule for 0.1 mL of 18% (v/v) ethanol. The dependent measures were response rate in responses/min and the dose of ethanol presented in g/kg. The points and vertical lines above “V” indicate the means and standard error of the mean (SEM) for sessions in which vehicle was administered (control). The points with vertical lines in the dose-effect data indicate the mean ± SEM for sessions in which DHEA was administered. The points without vertical lines indicate instances in which the SEM is encompassed by the point.
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