Advances in Pharmacological and Pharmaceutical Sciences / 2012 / Article / Tab 2

Review Article

An Overview of the CNS-Pharmacodynamic Profiles of Nonselective and Selective GABA Agonists

Table 2

Component tests of the Neurocart battery and the related CNS domains.

Neurocart testTargeted functionRelated CNS areas

Saccadic eye movementNeurophysiologic functionSuperior colliculus, substantia nigra, amygdala
Smooth pursuitNeurophysiologic functionMidbrain
Adaptive trackingVisuomotor coordinationNeocortex, basal nuclei, brain stem, cerebellum
Body swayBalanceCerebellum, brain stem
Visual verbal learning test (VVLT)MemoryHippocampus
VAS Bond and LaderAlertness, mood, calmnessCortex, prefrontal cortex
VAS BowdleFeeling high, internal and external perceptionCortex, prefrontal cortex, amygdala

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