Advances in Pharmacological and Pharmaceutical Sciences / 2012 / Article / Tab 3

Review Article

An Overview of the CNS-Pharmacodynamic Profiles of Nonselective and Selective GABA Agonists

Table 3

Use of pharmacodynamic tests in each study.

StudyCHDR99112CHDR0102CHDR0105CHDR0614CHDR0407
compoundTPA023TPACMP2SL65.1498AlprazolamZolpidem
comparatorLorazepamLorazepamLorazepamNANA

SEMDoneDoneDoneDoneDone
SwayDoneDoneDoneDoneDone
VAS BLDoneDoneDoneDoneDone
SmoothNDNDDoneDoneDone
TrackNDNDNDDoneDone

ND: not done; NA: not applicable; SEM: saccadic eye movement; Smooth: smooth pursuit; Sway: body sway; VAS BL: VAS Bond and Lader; Track: adaptive tracking.

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