Central Dopaminergic System and Its Implications in Stress-Mediated Neurological Disorders and Gastric Ulcers: Short Review

Table 1

Acute and chronic unpredictable stress-induced alterations in dopamine, prostaglandin E₂ levels, histopathological changes, and mean ulcer score in gastric tissues.

Parameters in gastric tissues	Models
	Nonstress	Acute stress	Chronic unpredictable stress
Dopamine levels	0	↓	↓↓
Prostaglandin E2	0	0	↓
Histopathological changes	0	↑	↑↑
Mean ulcer score	0	↑	↑↑
Plasma corticosterone	0	↑↑	↑

This information was obtained from our previous paper [39]. Plasma corticosterone was shown as stress marker. Symbols represent the following: 0: no effect, ↓: small decrease, ↓↓: large decrease, ↑: small increase, and ↑↑: large increase.