Analgesic and Anti-Inflammatory Activity of Pinus roxburghii Sarg.

Table 4

Protective efeect of Pinus roxburghii Sarg. on tail withdrawal reflex induced by tail immersion.

Groups	Drug (dose), route	Reaction time (min) Mean ± SEM
		30 min	60 min	90 min	120 min
Control	Tween 80 (5%), p.o	1.0±0.1	1.4±0.2	1.5±0.2	2.8±0.2
Standard	Diclofenac sodium (50 mg/kg), p.o	5.8±0.2^∗∗	8.2±0.2^∗∗	8.4±0.2^∗∗	8.8±0.2^∗∗
AB	100 mg/kg, p.o	1.4±0.2	2.4±0.3	2.8±0.2	3.4±0.2
AB	300 mg/kg, p.o	1.8±0.2	3.2±0.2^∗	4.4±0.4^∗	6.2±1.5^∗
AB	500 mg/kg, p.o	2.8±0.4^∗∗	3.2±0.4^∗	4.6±0.2^∗	5.4±1.9

𝑛=5. Results are expressed as mean ± SEM. ^∗𝑃>0.05, ^∗∗𝑃<0.01 as compared to control, AB = alcoholic bark extract.