Sedative and Hypnotic Activities of the Methanolic and Aqueous Extracts of Lavandula officinalis from Morocco

Table 2

Sedative effect of aqueous extract of Lavandula officinalis. p.o. means oral route; i.p. means intraperitoneal route; 𝑛 means number of mice per group; sec means seconds; AE means aqueous extract; DZP means diazepam. Data are expressed as mean ± SD; 𝑃<0.001 versus the control group.

Test		Control	Diazepam i.p.	Aqueous extract of Lavandula officinalis p.o.
			DZP; (3 mg/kg)	AE; (100 mg/kg)	AE; (200 mg/kg)	AE; (400 mg/kg)
Traction test	Re-establishment time	0.09 sec ± 0.0	10 sec ± 0.3	2 sec ± 0.3	12 sec ± 0.5*
		𝑛=5	𝑛=5	𝑛=5	𝑛=4
Fireplace test	Time to go back the tube in seconds	7 sec ± 0.5	>2 min	12 sec ± 0.1	45 sec ± 1*
		𝑛=5	𝑛=5	𝑛=5	𝑛=5
Hole-board test	Explored holes during 5 minutes	10±1	0.0±0.0	6±0.2	1 ± 0.0*
		𝑛=5	𝑛=5	𝑛=5	𝑛=4