Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair
The effects of PPE-induced injury (0.6 U/mL) and targeting beta1 integrin using JB1a (1 ug/mL) in comparison to K20 (1 ug/mL) clone on the kinetics of beta1 integrin levels on cell membrane in vitro using human lung coculture. (a) Western blot of the cell membrane expression of β1 integrin over time. Protein extracts were loaded at equal protein concentration (25 μg). (b) Densitometric analyses of the blot corrected using actin as an internal control.