Advances in Pharmacological and Pharmaceutical Sciences / 2012 / Article / Fig 7

Research Article

Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair

Figure 7

The effects of PPE-induced injury (0.6 U/mL) and targeting beta1 integrin using JB1a (1 ug/mL) in comparison to 6S6 clone (1 ug/mL) and the broad spectrum caspase inhibitor, ZVAD-fmk, on caspase 3/7 activation in vitro using human lung coculture during mechanical stretch ( ). Asterisks denotes statistical significance with * and ** in comparison to PPE.