Review Article

The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review

Table 2

Reported phytochemicals from genus Spilanthes.

Name of the plantType of nucleusName of the compoundPart used and methodReferences

Spilanthes acmella AlkamideSpilanthol 1, undeca-2E,7Z,9E-trienoic acid isobutylamide 2, and undeca-2E-en-8,10-diynoic acid isobutylamide 3, andHexane extract of dried flower buds [39]
Spilanthes acmella AlkamideSpilanthol 1, N-2-methylbutyldeca-2E, GZ, 8E-trienamide Q and -amyrm esters and sitosterol-O- -D-glucosldeWhole plant[43]
Spilanthes acmella Aliphatic compoundsLauric, myristic, palmitic linoleic, and linolenic acids as their methyl estersWhole plant[130]
Spilanthes acmella Sterols, coumarinVanillic acid 18, trans-ferulic acid 21, scopoletin 20, 3-acetylaleuritolic acid 17, -sitostenone 19, and mixture of stigmasteryl-and -sitosteryl-3-O- -D-glucopyranosidesAerial parts[2]
Spilanthes acmella Triterpenoidal saponin Olean-12-en-3-O-beta-D-galactopyranosyl (1→4)-O-alpha-L rhamnopyranoside Root[131]
Spilanthes acmella Long chain 2-ketol esterAcmellonate N-isobutyl-dodeca-2E,4E,8Z,l 0 E-tetraenamide 3Ethyl acetate extract Whole plant[132]
Spilanthes oppositifolia AlkamideSpilanthol 1Aerial parts[133]
Spilanthes alba Unsaturated amidesAcetylemc amidesAerial parts[134]
Spilanthes mauritiana AlkamideN-isobutyl-2E,4E,8E.lOZdodeca-2,4,8,1O-tetraenamideAerial parts [40]
Spilanthes leiocarpa Terpeniods Isocomene, lupeyl acetate, caryophyllen-l,l0-epoxide, and alantolactone, eudesmanolide 13Aerial parts [45]
Spilanthes ocymifolia Amides TerpenoidN-2-Phenylethylcinnamide, stigmasterol Taraxasterol acetate lupeyl acetateLeaves[42]
Spilanthes callimorpha Alkamides8,11-dihydroxy-dodeca-2E,4E, 9E-triensaureisobutylamide and 7-hydroxy-trideca-2E, 8E-dien-10, 12-diynoic acid isobutylamideWhole plant[135]
Spilanthes oleracea L.AlkamidesZ-Non-2-en-6,8-diynoic acid isobutylamide 3 and (Z)-dec-2-en-6,8-diynoic acid isobutylamideWhole plant[41]