Antimicrobial, Antioxidant, and Wound Healing Properties of Kigelia africana (Lam.) Beneth. and Strophanthus hispidus DC.

Table 3

Antimicrobial activity of methanol leaf extract (KAL) and stem bark extract (KASB) of K. africana and leaf extract (SHL) and root extract (SHR) of S. hispidus by agar diffusion method. Mean zones of growth inhibition (plus diameter of well) are mean (mm) of 3 independent experiments, mean ± SD, 𝑛=3 replicates, diameter of well/cup = 8 mm, reference antimicrobial agents: CPC: chloramphenicol (1 mg/mL), CTZ: clotrimazole (1 mg/mL), nd: not determined.

Mean zones of growth inhibition (mm)
Extract (mg/mL)	Test organisms
	S. aureus; ATCC 25923	B. subtilis; NCTC 10073	E. coli; ATCC 25922	P. aeruginosa; ATCC 27853	C. albicans
KAL
10	12.45 ± 0.50	12.50 ± 0.40	12.00 ± 0.50	0.0	15.50 ± 0.50
20	14.50 ± 0.50	13.53 ± 0.50	15.50 ± 0.25	12.50 ± 0.70	18.50 ± 0.55
50	16.35 ± 0.45	16.50 ± 0.35	19.65 ± 0.55	15.50 ± 0.70	23.35 ± 0.45
KASB
10	0.0	11.50 ± 0.25	12.50 ± 0.50	0.0	12.55 ± 0.55
20	13.00 ± 0.50	13.50 ± 0.45	16.55 ± 0.25	10.50 ± 0.50	15.50 ± 0.50
50	15.00 ± 0.55	15.00 ± 0.50	19.65 ± 0.25	14.50 ± 0.25	18.5 ± 0.25
SHL
10	11.00 ± 0.50	0.0	11.00 ± 0.50	0.0	12.50 ± 0.25
20	13.50 ± 0.55	12.50 ± 0.50	13.25 ± 0.50	14.50 ± 0.25	14.25 ± 0.25
50	16.55 ± 0.25	14.50 ± 0.25	17.50 ± 0.25	16.55 ± 0.50	18.25 ± 0.50
SHR
10	12.5 ± 0.50	12.55 ± 0.50	11.25 ± 0.50	0.0	12.50 ± 0.20
20	14.50 ± 0.50	15.50 ± 0.50	15.55 ± 0.50	13.00 ± 0.50	14.50 ± 0.50
50	18.25 ± 0.25	17.50 ± 0.25	17.00 ± 0.25	15.50 ± 0.25	16.50 ± 0.25
CPC	25.5 ± 0.25	31.50 ± 0.25	30.55 ± 0.25	17.50 ± 0.25	nd
CTZ	nd	nd	nd	nd	25.50 ± 0.50