Effects of Methanol Extract of Breadfruit (Artocarpus altilis) on Atherogenic Indices and Redox Status of Cellular System of Hypercholesterolemic Male Rats

Table 7

Changes in antiatherogenic, coronary risk, and cardioprotective indices of hypercholesterolemic rats treated with methanol extract of Artocarpus  altilis and Questran for nine weeks.

Treatment	Serum
	AAI (%)	CRI	CPI
Control	292.1±21.2	1.34±0.03	1.15±0.05
HC	28.0±3.7^∗	4.53±0.25^∗	0.40±0.06^∗
HC + AA1	27.2±2.7^∗	4.65±0.43^∗	0.30±0.05^∗
HC + AA2	116.1±17.3^∗∗	1.86±0.17^∗∗	0.89±0.15^∗∗
HC + QUE	143.0±21.8^∗∗	1.70±0.22^∗∗	0.72±0.08^∗∗
QUE	149.1±12.1	1.67±0.26	0.83±0.10
AA2	233.0±22.7	1.43±0.22	1.06±0.41

HC: cholesterol at 30 mg/0.3 mL, AA1: Artocarpus  altilis at 100 mg/kg,
AA2: Artocarpus  altilis at 200 mg/kg, QUE: questran at 0.26 g/kg,
antiatherogenic index (AAI): 100 × [HDL-C/total cholesterol−HDL-C],
coronary risk index (CRI): total cholesterol/HDL-C,
cardioprotective index (CPI): HDL-C/LDL-C.
*Significantly different from control (𝑃<0.05), **significantly different from HC (𝑃<0.05).