Advances in Pharmacological and Pharmaceutical Sciences / 2015 / Article / Tab 1

Research Article

Can Chronic Nitric Oxide Inhibition Improve Liver and Renal Dysfunction in Bile Duct Ligated Rats?

Table 1

Effect of different treatments on liver and renal functions of bile duct ligated rats.

TreatmentControlShamBDLAminoguanidineL-NAME

ALT24.3 ± 1.8 56.1 ± 2.1 1012# ± 6.4 290.2 ± 3.5 1517 ± 8.3
AST126.3 ± 5.9 310.4 ± 5.7 1379# ± 11.0 1102 ± 5.3 1801 ± 6.4
LDH929.7 ± 6.9 1637 ± 14.7 2607# ± 10.1 2050 ± 18.8 2428 ± 16.1
T. bilirubin0.02 ± 0.002 0.08 ± 0.003 4.06# ± 0.1 3.51 ± 0.04 6.07 ± 0.07
Urea11.8 ± 0.4 31.5 ± 0.8 327.7# ± 3.8 172.4 ± 2.7 516.4 ± 5.8
Creatinine0.24 ± 0.02 0.72 ± 0.05 2.72# ± 0.06 1.95 ± 0.06 2.78 ± 0.02

Data are presented as mean ± S.E., . Significantly different from control at , #significantly different from sham at , and significantly different from BDL at , using one-way ANOVA and Tukey’s post hoc test.

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