Research Article

Can Chronic Nitric Oxide Inhibition Improve Liver and Renal Dysfunction in Bile Duct Ligated Rats?

Table 2

Effect of different treatments on nitrosative and oxidative stress in bile duct ligated rats.

TreatmentControlShamBDLAminoguanidineL-NAME

MPO 1.8 ± 0.1 2.9 ± 0.2 4.6# ± 0.2 4.2 ± 0.3 4.5 ± 0.3
GSH 2.7 ± 0.2 1.6 ± 0.1 0.4# ± 0.1 0.9 ± 0.1 0.6 ± 0.1
MDA 24.6 ± 0.141.1 ± 1.3 62.7# ± 2.3 52.7 ± 2.6 58.2 ± 2.5
NO 0.21 ± 0.020.33 ± 0.030.94# ± 0.02 0.19 ± 0.020.08 ± 0.004

Data are presented as mean ± S.E., .  Significantly different from control at ,  #significantly different from sham at , and significantly different from BDL at , using one-way ANOVA and Tukey’s post hoc test.