Advances in Pharmacological and Pharmaceutical Sciences / 2015 / Article / Tab 2

Research Article

Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies

Table 2

Blood levels of ALT, BUN, and creatinine in hamsters treated with 5,3-hydroxy-7,4-dimethoxyflavanone.

GroupALT (U/L)BUN (mg/dL)Creatinine (mg/dL)

(A) TD0
 Healthy () 64.4 ± 5.615.9 ± 2.60.4 ± 0.1
 Infected/untreated ()73.9 ± 2.818.2 ± 1.90.4 ± 0.14
 Flavanone solution ()67.8 ± 3.218.0 ± 4.90.5 ± 0.1
 Flavanone cream ()65.8 ± 17.617.4 ± 1.30.3 ± 0.02
 MA (i.l) ()57.0 ± 6.120.9 ± 6.90.4 ± 0.1
(B) TD8
 Flavanone solution ()76.8 ± 3.720.0 ± 2.20.4 ± 0.03
 Flavanone cream ()77.1 ± 7.622.9 ± 6.40.3 ± 0.1
 MA (i.l) ()62.0 ± 8.523.8 ± 2.20.8 ± 0.1

Data represent the mean values ± SD of animals per group of treatment.

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