Changes in IL-2 and IL-10 during Chronic Administration of Isoniazid, Nevirapine, and Paracetamol in Rats

Table 3

Average (mean ± SD) change in renal and liver function tests during treatment of the rats with NVP, INH, and PAR over the study period.

Group	RFT		LFT
	BUN (mmol/l)	Cr (µmol/l)	ALT (U/l)	AST (U/l)	ALP (U/l)
Untreated
0 days
S
2 days
7 days
14 days
28 days
42 days
NVP
2 days
7 days
14 days
28 days
42 days
INH
2 days
7 days
14 days
28 days
42 days
PAR
2 days
7 days
14 days
28 days
42 days

RFT: renal function test; BUN: blood urea nitrogen; Cr: creatinine; LFT: liver function test; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; S: saline; INH: isoniazid; NVP: nevirapine; PAR: paracetamol; .