Protective Role of Ramipril and Candesartan against Myocardial Ischemic Reperfusion Injury: A Biochemical and Transmission Electron Microscopical Study

Table 2

Nitrate level in myocardial tissue.

S. number	Group	Tissue nitrate level (µg/dL)
1	Group I	52 ± 15.3
2	Group II	44 ± 2.3^#
3	Group III	48 ± 3.7
4	Group IV	50 ± 3.6
5	Group V	55 ± 7.4

All values were expressed as mean ± SEM, One-Way Analysis of Variance, followed by Dunnett’s versus Group I and ,  and   when compared with Group II.
Group I: rats treated with saline (10 mL/kg p.o).
Group II: rats treated with saline (10 mL/kg p.o) and subjected to in vitro global ischemia
Group III: rats treated with Ramipril (2 mg/kg p.o) and subjected to in vitro global ischemia.
Group IV: rats treated with Candesartan (1 mg/kg p.o) and subjected to in vitro global ischemia.
Group V: rats treated with combination of both drugs and subjected to in vitro global ischemia.