Research Article
Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery
Table 2
Maximal contractile response and pEC50 values to U46619 in rat renal arteries following organ culture for 24 h in presence of vehicle (DMSO) or different concentration of NF-κB inhibitors.
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Overview of and pEC50 values of U46619-induced contractile response on rat renal arteries. The segments were organ cultured for 24 h in presence of vehicle (control) or different concentrations of MG-132 (MG 0.2, 1, or 5 μM) or BMS345541 (BMS 1, 5, or 25 μM). Data are shown as mean ± SEM. denotes the number of vessel segments. One-way ANOVA with Dunnett’s multiple comparison test was used. , , versus vehicle. |