Table 1: Effect of the root extract of U. chamae on blood glucose (mg/dl) in alloxan-induced diabetes mellitus and percentage reduction in blood glucose (%).

DaysControl (2% acacia)Glibenclamide (71 µg/kg)Pioglitazone (429 µg/kg)UC (100 mg/kg)UC (250 mg/kg)UC (400 mg/kg)Diabetic untreated

086.75 ± 2.3676.00 ± 3.2283.33 ± 9.2088.33 ± 3.7671.33 ± 3.7677.67 ± 4.2665.33 ± 5.90
191.75 ± 1.93357.7 ± 28.30352.3 ± 9.40359.0 ± 16.10337.3 ± 6.70501.7 ± 56.30264.0 ± 5.80
382.00 ± 3.20222.3 ± 51.40 (37.85)239.0 ± 38.40 (32.16)284.7 ± 22.40 (20.70)270.7 ± 18.8 (19.75)280.3 ± 8.30 (44.13)272.0 ± 2.00 (−3.03)
584.00 ± 3.00189.0 ± 48.80 (47.16)173.7 ± 35.80 (50.70)198.7 ± 64.30 (44.65)94.0 ± 7.50 (72.13)157.0 ± 61.10 (68.71)282.3 ± 1.50 (−6.93)
778.25 ± 4.27132.0 ± 16.80 (63.10)245.0 ± 59.81 (30.46)100.0 ± 11.68 (72.14)71.67 ± 9.17 (78.75)61.67 ± 1.86 (87.71)288.7 ± 0.88 (−9.36)
990.25 ± 3.10117.0 ± 11.90 (67.29)275.3 ± 48.40 (21.86)91.67 ± 13.60 (74.47)70.33 ± 8.70 (79.15)58.33 ± 6.40 (88.37)297.7 ± 1.20 (−12.77)
1184.75 ± 2.50109.3 ± 10.30 (69.44)202.3 ± 70.50 (42.58)90.33 ± 9.20 (74.84)73.0 ± 4.00 (78.36)50.33 ± 7.40 (89.97)305.3 ± 4.80 (−15.64)
1383.50 ± 4.90100.0 ± 7.50 (72.04)145.7 ± 77.70 (58.64)79.0 ± 10.70 (77.99)68.33 ± 2.00 (79.74)55.0 ± 7.60 (89.04)312.7 ± 9.20 (−18.45)
1579.75 ± 3.5093.0 ± 5.60 (74.00)158.3 ± 59.30 (55.07)75.0 ± 10.00 (79.11)72.33 ± 4.30 (78.56)59.67 ± 6.40 (88.11)318.7 ± 11.30 (−20.72)

Significant difference (; ) between the mean ± SEM of test groups vs. control. UC: Uvaria chamae.