Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

Figure 4

Apoptosis induction through the activation of caspase 3/7 after treatment with various compounds in HCT116 cells was determined as % live, % early, and late apoptosis and % dead cells by the MUSE cell analyzer. (a) Normal control; (b) normal control; (c) SAHA (5 μM); (d) quercetin (100 μM); (e) QMJ-2 (100 μM); (f) QMJ-5 (50 μM).

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