Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

<div>Effect of various compounds on different phases of HCT116 cells was estimated using flow cytometer. Histogram plots display the different phases of the cell cycle and the percentage of cells in each phase. (a) Normal control; (b) SAHA (5 <i>μ</i>M); (c) quercetin (100 <i>μ</i>M); (d) QMJ-2 (100 <i>μ</i>M); (e) QMJ-5 (50 <i>μ</i>M).</div>

Advances in Pharmacological and Pharmaceutical Sciences

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Figure 5

Figure 5: Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer 