Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

Table 1

MTT assay.

Sl. no.	Compound	IC50 (µM ± SEM)
		HCT116	Vero
1	QMJ-1	102.5 ± 1.8	186.4 ± 4.9
2	QMJ-2	68 ± 2.3	140 ± 6.8
3	QMJ-3	70.3 ± 4.1	80.1 ± 3.7
4	QMJ-4	>400	>400
5	QMJ-5	27.4 ± 1.8	55.6 ± 3.8
6	QMJ-6	94 ± 2.1	153 ± 2.3
7	Quercetin	107.6 ± 1.2	201.5 ± 7.5
8	SAHA	3.1 ± 0.35	4.6 ± 1.6

All values are expressed as mean ± SEM of three experiments.