Research Article
Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs
Figure 7
Morphometric assessment of the heart. (a) Mean heart weight-to-body weight ratio. (b) Mean ventricular wall thickness (mm) of dogs given normal saline, cumulative dose of free doxorubicin 150 mg/m2, CS-CaCO3NP-DOX 250 mg/m2, CS-CaCO3NP-DOX 150 mg/m2, and CS-CaCO3NP-DOX 100 mg/m2 (). is considered statistically significant between the groups.
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