Synthesis and Pharmacological Valorization of Derivatives of 4-Phenyl-1,5-Benzodiazepin-2-One

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center">Witness thiopental sodium (40 mg/kg)</td><td class="align_center">Thiopental sodium (40 mg/kg) + 4-phenyl-1,5-benzodiazepin-2-one (100 mg/kg)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">TE (s)</td><td class="align_center">180 ± 60</td><td class="align_center">143.40 ± 33.33</td></tr><tr><td class="align_left">TS (min)</td><td class="align_center">45 ± 20</td><td class="align_center">140.60 ± 104.03</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

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Advances in Pharmacological and Pharmaceutical Sciences

tab4

Table 4

Table 4: Synthesis and Pharmacological Valorization of Derivatives of 4-Phenyl-1,5-Benzodiazepin-2-One 