Phenolic Rich Fractions from Mycelium and Fruiting Body of <i>Ganoderma lucidum</i> Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line

<div>Cellular viability as determined by MTT assay. GLMph (100 <i>µ</i>g/ml), GLMdee (75 <i>µ</i>g/ml), GLFph (50 <i>µ</i>g/ml), GLFdee (100 <i>µ</i>g/ml), and GLFea (50 <i>µ</i>g/ml) improved cellular viability to 57%, 65.5%, 67.52%, 58.73%, and 75%, under hypoxia. N: normoxia, N + sample: normoxia supplemented with respective phenolic rich fraction of <i>Ganoderma lucidum</i> fruiting body or mycelium, H: hypoxia, H + E: hypoxia supplemented with respective phenolic rich fraction of <i>Ganoderma lucidum</i> fruiting body or mycelium (numbers in parentheses indicate the corresponding optimal dose for each phenolic rich fraction).</div>

Advances in Pharmacological and Pharmaceutical Sciences

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Figure 5

Figure 5: Phenolic Rich Fractions from Mycelium and Fruiting Body of <i>Ganoderma lucidum</i> Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line 

Figure 5 | Phenolic Rich Fractions from Mycelium and Fruiting Body of Ganoderma lucidum Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line 