Evaluation of Anti-HIV-1 Integrase and Anti-Inflammatory Activities of Compounds from Betula alnoides Buch-Ham

Figure 2

Molecular docking of the isolated compounds with HIV-1 IN. The ribbon model shows the backbone of the HIV-1 IN catalytic domain with all interacting amino acid residues shown as stick models and colored by heteroatoms. H-bond interactions are shown as red dashed lines and represent bond length in angstroms (Å). Mg²⁺ ions are shown as green balls. (a) Betulinic acid (1), (b) betulin (2), (c) lupeol (3), (d) oleanolic acid (4), and (e) ursolic acid (5).

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