Protective Effects of Aqueous Extract of Baillonella toxisperma Stem Bark on Dexamethasone-Induced Insulin Resistance in Rats
Table 1
Effect of Baillonella toxisperma on biochemical parameters in dexamethasone-induced insulin resistance in rats.
Total proteins (g/dL)
Total cholesterol (mg/dL)
Triglycerides (mg/dL)
HDL cholesterol (mg/dL)
LDL cholesterol (mg/dL)
ALT (U/L)
AST (U/L)
Normal control
6.52 ± 0.42
58.85 ± 4.93
51.25 ± 7.51
33.08 ± 2.946
15.52 ± 6.472
39.99 ± 5.31
30.19 ± 2.49
Dex control
4.78 ± 0.29
97.94 ± 2.60
85.71 ± 2.52
13.30 ± 0.59
67.50 ± 2.55
78.81 ± 4.19
112.5 ± 5.60
Dex + Metf (40 mg/kg)
5.26 ± 0.54
70.60 ± 4.07c
49.64 ± 6.03c
17.22 ± 0.36
43.46 ± 3.75
54.19 ± 5.39
43.94 ± 5.14c
Dex + AEBT (60 mg/kg)
5.12 ± 0.20
70.45 ± 4.37c
65.71 ± 5.29
19.67 ± 2.02
37.63 ± 4.81
119.7 ± 5.80
120.3 ± 12.72
Dex + AEBT (120 mg/kg)
5.86 ± 0.45
88.76 ± 3.07
46.32 ± 5.32c
21.84 ± 1.98
57.65 ± 4.26
62.22 ± 6.71
79.29 ± 9.37
Dex + AEBT (240 mg/kg)
5.72 ± 0.39
91.93 ± 3.35
49.45 ± 5.28c
24.87 ± 2.53b
57.18 ± 3.60
17.34 ± 6.81c
73.30 ± 3.53b
Dex: dexamethasone; AEBT: aqueous extract of B. toxisperma; Metf: metformin. ,, and compared to the normal control group; ,, and compared to the dexamethasone control group. ; data are presented as mean ± SEM.