Research Article

Protective Effects of Aqueous Extract of Baillonella toxisperma Stem Bark on Dexamethasone-Induced Insulin Resistance in Rats

Table 1

Effect of Baillonella toxisperma on biochemical parameters in dexamethasone-induced insulin resistance in rats.

Total proteins (g/dL)Total cholesterol (mg/dL)Triglycerides (mg/dL)HDL cholesterol (mg/dL)LDL cholesterol (mg/dL)ALT (U/L)AST (U/L)

Normal control6.52 ± 0.4258.85 ± 4.9351.25 ± 7.5133.08 ± 2.94615.52 ± 6.47239.99 ± 5.3130.19 ± 2.49
Dex control4.78 ± 0.2997.94 ± 2.6085.71 ± 2.5213.30 ± 0.5967.50 ± 2.5578.81 ± 4.19112.5 ± 5.60
Dex + Metf (40 mg/kg)5.26 ± 0.5470.60 ± 4.07c49.64 ± 6.03c17.22 ± 0.3643.46 ± 3.7554.19 ± 5.3943.94 ± 5.14c
Dex + AEBT (60 mg/kg)5.12 ± 0.2070.45 ± 4.37c65.71 ± 5.2919.67 ± 2.0237.63 ± 4.81119.7 ± 5.80120.3 ± 12.72
Dex + AEBT (120 mg/kg)5.86 ± 0.4588.76 ± 3.0746.32 ± 5.32c21.84 ± 1.9857.65 ± 4.2662.22 ± 6.7179.29 ± 9.37
Dex + AEBT (240 mg/kg)5.72 ± 0.3991.93 ± 3.3549.45 ± 5.28c24.87 ± 2.53b57.18 ± 3.6017.34 ± 6.81c73.30 ± 3.53b

Dex: dexamethasone; AEBT: aqueous extract of B. toxisperma; Metf: metformin. , , and compared to the normal control group; , , and compared to the dexamethasone control group. ; data are presented as mean ± SEM.