Formulation and Optimization of Monolithic Fixed-Dose Combination of Metformin HCl and Glibenclamide Orodispersible Tablets

Table 3

Experimental levels of the independent variables for preliminary formulations.

Variables	Levels
	Minimum (−1)	Maximum (+1)
PEG 6000 (%)	2	7
Crospovidone (%)	2	10
Compression force (kN)	5	15