Current Status of Alginate in Drug Delivery

Table 2

Alginate nano/microparticles with protein content.

Protein types	Polymer	Method for encapsulation	Significant findings	References
Salmonella effector enzyme (AvrA)	Alginate-chitosan	Microfluidics	Capable of releasing AvrA NPs in the small intestine and colon	[97]
Silk fibroin	Alginate and PLGA	Layer-by-layer deposition	Silk coatings provide stable-encapsulated protein	[98]
Bovine serum albumin	Alginate-poloxamer	Spray drying	Spherical in shape with a size range of 4–6 μm and faster protein release	[99]
Bovine serum albumin	Alginate	Microemulsions-based reactors	Microemulsions of 6 nm stabilized the protein	[100]
Dextran-HEMA	Alginate	Partial oxidation	Good gelling ability	[101]