Development and Validation of the Quantification Method for Hydroxychloroquine in Volumetric Absorptive Microsampling (VAMS) Using High-Performance Liquid Chromatography-Photodiode Array

Table 3

Data of accuracy and precision, within-run, and between-run.

Nominal concentration (ng/mL)	Day	Within-run			Between-run
		Mean measured concentration (ng/mL)	CV (%)	% difference (range)	Mean measured concentration (ng/mL)	CV (%)
LLOQ (2.00)	1	1.97	10.07	−17.01–7.69	1.97	9.24
	2	1.98	11.42	−14.20–16.67
	3	1.97	8.17	−11.91–8.79
QCL (6.00)	1	5.71	6.15	−9.67–5.92	5.92	7.15
	2	5.91	8.30	−11.19–7.42
	3	6.15	6.12	−3.66–10.11
QCM (2,600)	1	2632.53	7.19	−5.15–11.50	2605.69	8.12
	2	2434.37	6.92	−12.02–3.57
	3	2750.18	6.17	−0.98–14.06
QCH (4,785)	1	5110.59	5.97	−4.45–12.95	4903.42	9.46
	2	4504.87	7.82	−12.86–4.78
	3	5094.81	9.58	−12.19–13.18