Ascorbic Acid Significantly Decreases Creatine Kinase Plasma Levels in an Animal Model of Statin/Fibrate-Induced Myopathy

Figure 2

Plasma creatine kinase (CK) levels of rats in the control and treated groups. ATV, atorvastatin (80 mg/kg/day for 10 days); GMF, gemfibrozil (1000 mg/kg/day for 10 days); Vit. C, ascorbic acid (50 mg/kg/day for 10 days). Swimming was done in days 8, 9, and 10. The levels of each bar are mean, and the error bar is SEM (n = 6 in each group). ^∗∗∗ value <0.001 compared with all of the other groups. One-way ANOVA followed by Tukey’ post hoc test.