Anderson–Fabry Disease: From Endothelial Dysfunction to Emerging Therapies

Figure 2

Possible mechanisms of endothelial dysfunction in Anderson–Fabry disease. IMT: intima-media thickness; NADPH: nicotinamide adenine dinucleotide phosphate; eNOS: endothelial nitric oxide synthase; RAS: renin-angiotensin system; RNS: reactive nitrogen species; ROS: reactive oxygen species.