Review Article
Thermosensitive Chitosan-β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications
Table 2
Factors influencing gelation, chitosan-β-glycerophosphate.
| MW | Con | DDA % | Time (min) | pH | GP | T (°C) | Drug | Reference |
| 310–375 | 0.8 g | 103 | 5 | 7 | 2 g | 37 | Aspirin | [64] | 62 | 0.1% | 82 | 1.6 | 7.4 | 12% | 30 | Mitomycin-c | [65] | 124 | 0.1% | 72 | 1.4 | 7.4 | 12% | 29.8 | Mitomycin-c | [65] | 370 | 0.1% | 71 | 1 | 7.4 | 12% | 29.6 | Mitomycin-c | [65] | 650 | 20 mg/mL | 85 | 10 | 7.35 | 3% | 37 | Curcumin | [66] | 200 | 1.8% | 91 | 12 | 6.88 | 9 | 37 | Docetaxel | [67] | 200 | 1.8% | 91 | 5 | 6.97 | 12 | 37 | Docetaxel | [67] | 200 | 1.4% | 91 | >120 | 6.75 | 6 | 37 | Docetaxel | [67] | 200 | 1.4% | 91 | 61 | 6.83 | 9% | 37 | Docetaxel | [67] | 306.12 | 2%% | 95 | 2 | 7.63 | 14% | 37 | Insulin | [68] | 306.12 | 2%% | 95 | 3 | 7.52 | 12% | 37 | Insulin | [68] | 306.12 | 2%% | 95 | 5 | 7.45 | 10% | 37 | Insulin | [68] | 306.12 | 2%% | 95 | 14 | 6.91 | 5% | 37 | Insulin | [68] |
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