In Vitro Comparative Quality Assessment of Different Brands of Doxycycline Hyclate Finished Dosage Forms: Capsule and Tablet in Jimma Town, South-West Ethiopia
Table 3
Model-independent approaches results of doxycycline hyclate 100 mg brands.
Sample code
f2
f1
DE (%)
%DE difference
MDT
MDT ratio
Mean % release ratio
SD % release ratio
RSD % release ratio
D01
64
13
93.3
2.9
3.01
0.66
1.13
0.07
5.71
D02
40
18
90.3
0.1
4.32
0.88
1.08
0.19
17.47
D04
57
7
86.3
4.1
6.19
1.04
0.94
0.14
15.27
D05
38
14
94.1
3.7
2.68
0.45
1.17
0.24
20.52
D06
57
8
84.0
6.4
7.20
0.95
1.05
0.09
8.10
D07
59
6
87.1
3.3
5.81
0.83
1.07
0.08
7.39
D09
41
10
69.9
2.3
3.61
1.09
0.91
0.06
1.09
D10
29
22
61.0
11.2
4.18
1.23
0.77
0.04
1.23
SD: standard deviation; RSD: relative standard deviation. %DE—D03, 90.4%; D08, 72.2. MDT—D03, 4.22; D08, 3.33.
