Advances in Pharmacological and Pharmaceutical Sciences / 2021 / Article / Tab 2

Research Article

Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl4-Induced Hepatic Damage in Wistar Rats

Table 2

Effect of aqueous extract of Caralluma europaea on CCl4-induced lipid profile changes in rats.

Treatment (n = 6)Cholesterol (g/L)Triglycerides (g/L)HDL (g/L)LDL (g/L)VLDL (g/L)Glucose (g/L)

Normal control0.59 ± 0.040.38 ± 0.030.23 ± 0.010.28 ± 0.020.07 ± 0.001.04 ± 0.03
CCl4 (1 mL/kg )0.58 ± 0.010.64 ± 0.060.18 ± 0.000.26 ± 0.010.12 ± 0.011.57 ± 0.06
CCl4 + AECe (250 mg/kg)0.54 ± 0.03 Ns0.31 ± 0.02Ns0.21 ± 0.01Ns0.26 ± 0.04 Ns0.06 ± 0.00Ns1.33 ± 0.04 Ns
AECe (250 mg/kg)0.52 ± 0.040.30 ± 0.020.22 ± 0.010.23 ± 0.040.06 ± 0.001.07 ± 0.06
CCl4 + silymarin (40 mg/kg)0.55 ± 0.030.34 ± 0.010.24 ± 0.010.21 ± 0.030.05 ± 0.011.22 ± 0.05

Values are expressed as mean ± SEM, (n = 6). Data were analyzed by one-way ANOVA followed by Tukey’s test.  when compared to the normal control group;  when compared to the normal control group.  when compared to the CCl4 group;  when compared to the CCl4 group. Ns = not significant when compared to the CCl4 + silymarin group.