Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl₄-Induced Hepatic Damage in Wistar Rats

Table 2

Effect of aqueous extract of Caralluma europaea on CCl₄-induced lipid profile changes in rats.

Treatment (n = 6)	Cholesterol (g/L)	Triglycerides (g/L)	HDL (g/L)	LDL (g/L)	VLDL (g/L)	Glucose (g/L)
Normal control	0.59 ± 0.04	0.38 ± 0.03	0.23 ± 0.01	0.28 ± 0.02	0.07 ± 0.00	1.04 ± 0.03
CCl4 (1 mL/kg )	0.58 ± 0.01	0.64 ± 0.06	0.18 ± 0.00	0.26 ± 0.01	0.12 ± 0.01	1.57 ± 0.06
CCl4 + AECe (250 mg/kg)	0.54 ± 0.03 Ns	0.31 ± 0.02^Ns	0.21 ± 0.01^Ns	0.26 ± 0.04 Ns	0.06 ± 0.00^Ns	1.33 ± 0.04 ^Ns
AECe (250 mg/kg)	0.52 ± 0.04	0.30 ± 0.02	0.22 ± 0.01	0.23 ± 0.04	0.06 ± 0.00	1.07 ± 0.06
CCl4 + silymarin (40 mg/kg)	0.55 ± 0.03	0.34 ± 0.01	0.24 ± 0.01	0.21 ± 0.03	0.05 ± 0.01	1.22 ± 0.05

Values are expressed as mean ± SEM, (n = 6). Data were analyzed by one-way ANOVA followed by Tukey’s test.  when compared to the normal control group;  when compared to the normal control group.  when compared to the CCl₄ group;  when compared to the CCl₄ group. Ns = not significant when compared to the CCl₄ + silymarin group.